what is the clinical features of pulmonary hypertension?
Clinical Features of Pulmonary Hypertension (PH)
Pulmonary hypertension often develops gradually, and symptoms may be non-specific in the early stages. As the disease progresses, signs and symptoms reflect right-sided heart strain and reduced oxygenation.
Symptoms (What the patient feels)
Symptom | Description |
---|---|
Dyspnea (shortness of breath) | Most common and early symptom; worsens with exertion |
Fatigue | Due to reduced cardiac output |
Chest pain or tightness | Especially during exertion (may mimic angina) |
Palpitations | Irregular heartbeats due to right atrial strain |
Syncope or dizziness | Especially on exertion; due to low blood flow to the brain |
Edema | Swelling in legs, ankles, feet—due to right heart failure |
Abdominal bloating or fullness | Due to hepatic congestion (enlarged liver) |
Cough and hemoptysis (rare) | May occur due to pulmonary artery rupture or infarct |
Signs (What is observed during examination)
Sign | Clinical Finding |
---|---|
Loud P2 | Accentuation of the second heart sound (pulmonary component) |
Right ventricular heave | Palpable impulse at the left parasternal area (RV hypertrophy) |
Jugular venous distension (JVD) | Elevated jugular veins from right-sided heart failure |
Peripheral edema | Pitting edema in the lower limbs |
Hepatomegaly | Enlarged, tender liver due to congestion |
Ascites | Fluid in the abdomen (late stage) |
Cyanosis | Bluish discoloration from hypoxemia (advanced disease) |
Tricuspid regurgitation murmur | Systolic murmur over lower left sternal border |
Functional Classification (WHO/NYHA)
Pulmonary hypertension is also classified by functional limitation:
Class | Description |
---|---|
I | No limitation of physical activity |
II | Mild limitation; comfortable at rest, symptoms on ordinary activity |
III | Marked limitation; comfortable at rest, symptoms on less than ordinary activity |
IV | Symptoms at rest; severe limitation of physical activity |
Complications
-
Right heart failure (cor pulmonale)
-
Arrhythmias
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Sudden cardiac death
-
Hemoptysis (rare but serious)
-
Pulmonary embolism (in chronic thromboembolic PH)
Quick Summary
Early Features | Dyspnea, fatigue, chest discomfort |
---|---|
Progressive Features | Syncope, peripheral edema, cyanosis |
Signs of Right Heart Failure | JVD, hepatomegaly, leg swelling |
Auscultation Findings | Loud P2, murmur of tricuspid regurgitation |
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